site stats

Cd81分子量大小

Web在巨噬细胞中，cd9功能与cd81以及β-1和β-2整合素相关，并阻止巨噬细胞融合成多核巨细胞，多核巨细胞专门吞噬补体调理大颗粒。 CD9参与血小板活化和聚集，它还参与细胞粘 … CD81 molecule, also known as CD81 (Cluster of Differentiation 81), is a protein which in humans is encoded by the CD81 gene. It is also known as 26 kDa cell surface protein, TAPA-1 (Target of the Antiproliferative Antibody 1), and Tetraspanin-28 (Tspan-28). See more The gene is located on the plus strand of the short arm of chromosome 11 (11p15.5). It is 20,103 bases in length and encodes a protein of 236 amino acids (predicted molecular weight 25.809 kDa). The protein does … See more The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of … See more CD81 has been shown to interact with TSPAN4, CD19, CD9, PTGFRN, CD117 and CD29. Ligands Benzyl salicylate and terfenadine have been shown to bind to CD81. See more • CD81+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Human CD81 genome location and CD81 gene details page in the UCSC Genome Browser. This article … See more This protein plays a critical role in Hepatitis C attachment and/or cell entry by interacting with virus' E1/E2 glycoproteins heterodimer. The large extracellular loop of CD81 binds the hepatitis E2 glycoprotein dimer. HCV-E2 and CD81 binding Kd is 1.8 … See more • Cluster of differentiation See more • Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye". J. Cell Sci. 114 (Pt 23): 4143–51. doi:10.1242/jcs.114.23.4143. PMID 11739647. • Ye J (2007). "Reliance of Host Cholesterol Metabolic Pathways for the Life Cycle of Hepatitis C Virus" See more

Clinical significance of CD81 expression by clonal plasma

WebDec 1, 2024 · CD81 is a four-transmembrane protein that is composed of two extracellular loops and three short intracellular domains. 1–3) CD81 belongs to the tetraspanin family, which modulates biological processes such as cell adhesion, motility, activation and proliferation. Tetraspanin molecules can laterally associate with one another and cluster … Web从细胞培养物中富集的总外泌体（使用“总外泌体分离”试剂或超速离心）可以通过免疫磁珠捕获进一步纯化特定的亚群。使用基于Dynabeads的CD9、CD63、CD81或EpCam特异性试剂，或将链霉亲和素试剂与您选择的生物素化抗体结合，以基于表面抗原纯化所有群体。 joplax エアガン https://mrfridayfishfry.com

UniProt

Webcd81 属于四跨膜蛋白家族，该家族蛋白有四个跨膜结构域、一个较短的胞外域 (ecl1) 和一个较长的胞外域 (ecl2) (1-3)。 四次跨膜蛋白在特化的四次跨膜蛋白富集微结构域 (TEMs) … WebAlix 是系统发育中保守的胞质支架蛋白，包含一个氨基末端 Bro1 结构域、一个卷曲螺旋域和一个羧基末端脯氨酸富集结构域 (1,2)。. Alix 最初被鉴定为 ALG-2（凋亡连接基因 2）互 … Web找cd81规格参数技术文档，厂家，现货等，上阿里巴巴ic专业市场。为你找到2,464条cd81型号，品牌，封装，批号，价格，图片等信息，批发采购cd81，上阿里巴巴1688 ic频道。 jooto タスク管理

Nature：从结构上揭示丙型肝炎病毒进入人细胞机制，有助于开发出HCV疫苗 …

Category:研究解析CD81-CD19的-cryo-EM结构—小柯机器人—科学网

Tags:Cd81分子量大小

Cd81分子量大小

CD81, a new actor in the development of preeclampsia

WebJun 7, 2024 · Anti-human CD81 5A6 mAb inhibits human breast cancer invasion and migration in vitro. (A and B) 3 × 10 3 MDA-MB-231 or (C) MDA-MB-436 cells were seeded in a 96-well round-bottom plate in 1× spheroid formation ECM and incubated for 48 to 72 h to promote sphere formation.Then invasion matrix was added containing 10 µg/mL of anti … WebOct 14, 2024 · 同时，作者观测到cd81缺失会加剧小鼠因高脂饮食诱导产生的肥胖，糖耐受能力减弱等表型。更为重要的是， 在人的皮下脂肪中，cd81+ apcs减少会显著增加患代谢疾病的风险。 图五：cd81对于cd81+ apcs分化成米色脂肪细胞是必需的。 a：构建cd81基因敲除 …

Cd81分子量大小

Did you know?

WebApr 6, 2024 · Tetraspanin CD81 plays major roles in cell-cell interactions and the regulation of cellular trafficking. This cholesterol-embarking transmembrane protein is a co-receptor for several viruses, including HCV, HIV-1 and Chikungunya virus, which exploits the large extracellular loop EC2 for cell entry. CD81 is also an anticancer target implicated in … WebCD81 is a tetraspanin cell surface protein that regulates CD19 expression in B lymphocytes and enables hepatitis C virus infection of human cells. Immunohistologic analysis in normal hematopoietic tissue showed strong staining for CD81 in normal germinal center B cells, a cell type in which its incr …

WebMar 13, 2012 · 检测CD抗原是识别细胞及不同分化阶段细胞或细胞亚群最主要的方法。. 人类CD抗原编码已从CD1至CD166，与T细胞识别、粘附、活化有关的CD分子主要有CD3、CD4、CD8、CD2、CD28、CD58和CD40L；与B细胞识别、粘附、活化有关的CD分子主要有CD79、CD19、CD21、CD81、CD80、CD86和CD40 ... WebApr 24, 2024 · Anti-CD81 antibody has short-term effects on TNBS-induced colitic mice. The effect of an anti-CD81 antibody on acute intestinal inflammation was examined in mice with acute colitis.

WebMar 13, 2007 · CD81的结构：CD81是TM4SF成员,为分子量为25kD的跨膜四分子蛋白,它表达广泛,在90%Burkitt淋巴瘤细胞株细胞表现有表达。. 它四次跨越细胞膜，在细胞外形成大小两个环状结构。. CD81在细胞内和跨细胞膜区域成分高度保守，而其大的细胞外环区域（EC2）具有易变性，在 ... WebNov 30, 2012 · CD81 (TAPA-1) is a ubiquitously expressed tetraspanin protein identified as a component of the B lymphocyte receptor (BCR) and as a receptor for the Hepatitis C Virus. In an effort to identify trans-membrane proteins that interact with the T-cell antigen receptor (TCR), we performed a membrane yeast two hybrid screen and identified CD81 as an …

WebMar 3, 2024 · CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation ...

WebMar 8, 2024 · Foxl1+ 特洛细胞（ Nature ， 2024 ）及 CD81+ 滋养细胞 (Cell Stem Cell ， 2024) 的发现，提示肠道可能存在多种分化不同且功能特异的肠道间质细胞亚群。 目前领域里对不同肠道间质细胞亚群的特征、空间分布、它们在组织损伤修复中的潜在功能、以及调节的细胞和分子机制仍知之甚少。 joplinapp オープンソースWebCD81 Antibodies. Antibodies that detect CD81 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and Immunoprecipitation. These antibodies target CD81 in Human, Mouse, Rat, Feline and Rabbit samples. Our CD81 monoclonal, polyclonal and … jooyi かわいいWebApr 15, 2024 · CD81 has also been shown to regulate cell migration and invasion, and has therefore been implicated in cancer progression. Indeed, we have recently shown that … jopsnet オカモトヤWebBiochem/physiol Actions. CD81 is a tetraspanin protein belonging to the novel Ig superfamily. It is expressed in several immune cells including T, B, and NK lymphocytes, monocytes, hepatocytes, and most stromal and epithelial cells. It forms a complex with other proteins including CD21, CD19, and CD225 at the time of B cell maturation. adelphi university googleWebApr 27, 2024 · Prior studies have suggested that the first TM helix of CD81 is the main specificity determinant for trafficking of CD19 to the cell surface (Shoham et al., 2006), but this claim has also been called into question (Berditchevski and Odintsova, 2007).To determine which regions of CD81 are necessary for trafficking CD19 to the cell surface, … jooto 使ってみたWebMar 21, 2024 · CD81 (CD81 Molecule) is a Protein Coding gene. Diseases associated with CD81 include Immunodeficiency, Common Variable, 6 and Common Variable Immunodeficiency.Among its related pathways are Complement cascade and Innate Immune System.Gene Ontology (GO) annotations related to this gene include MHC … jooto ダウンロードWeb设立分化簇 (CD) 命名系统的目的是对白细胞表面抗原进行分类。. 最初，表面抗原是根据与它们结合的对应单克隆抗体进行命名。. 随着各实验室逐渐发现抗原常能刺激产生多种单 … jooto プロジェクト 削除