Galectin-12
WebMar 29, 2024 · Title: Galectin-12 inhibits granulocytic differentiation of human NB4 promyelocytic leukemia cells while promoting lipogenesis. Lower LGALS12 gene … Webgalectin-12 was augmented in adipose tissue of animals under caloric restriction and treatment with a synthetic peroxisome proliferator-activated receptor (PPAR) ligand, …
Galectin-12
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WebApr 13, 2024 · Time: 9:00 am – 12:00 pm ET Location: Poster Section 35 Poster Number: 20. Abstract LB173 Title: A bioinformatics approach to determine the potential benefit of … WebGalactin-12 is an adipocyte-expressed protein and possesses adipocyte-inducing activity. We investigated the expression level of candidate proteins involved in galactin-12-mediated adipocyte differentiation pathway. We performed a high-throughput screening assay to monitor galectin-12 promoter activity using 105 traditional Chinese herbs.
WebApr 1, 2012 · Galectin-12, a two-CRD galectin, was cloned a decade ago by this laboratory. 6 Like other galectin genes, galectin-12 gene (Lgals12) does not encode a … Web52 minutes ago · Galectin Inhibitors Drugs Have Emerged As New Focused Domain For Cancer Clinical Researchers Says Kuick ResearchDelhi, April 14, 2024 (GLOBE NEWSWIRE) -- Global Galectin Inhibitors Market Trends ...
WebTo date, 12 members of the galectin family have been isolated from various tissues and cells in mammals (3–14). The members of the galectin family share a common structure, a highly conserved carbohydrate-recognition domain (CRD), 1 consisting of ∼135 amino acid residues. The prototype galectins (galectins -1, -2, -5, -7, -10, and -11) contain a single … WebGalectins, a family of animal lectins characterized by their affinity for N-acetyllactosamine-enriched glycoconjugates, modulate several immune cell processes shaping the course …
WebSep 20, 2014 · Galectin-1, -3, -8 and -9 are found on cells of the hematopoietic lineage as well as in endothelial cells (6,11,14,20). Galectin-2, -4, -7 and -9 are expressed in different epithelia and galectin-12 is almost exclusively found in adipose tissue . Galectin expression is also modulated throughout cell activation, inflammation and in pathologic ...
WebBackground. LGALS12, also known as Galectin-12, is a protein with 6 isoforms ranging from 266 amino acid and 30 kDa to 366 amino acid and 38 kDa; predominantly … top golf courses in utahWebOct 15, 2007 · Indeed, the presentation of galectin-1 by activated ECs triggers apoptosis of activated T cells. 16,64,65 Galectin-3 and galectin-9 are also able to induce T-cell apoptosis. 66-68 Furthermore, galectin-3 can inhibit T-cell activation by complexing with the T-cell receptor. 69 Thus, up-regulation of galectin expression by ECs may provide a ... top golf courses in west palm beachWebGalectin-12 is a member of the galectin family consisting of β-galactoside-binding proteins with conserved carbohydrate recognition domains. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes. We previously showed that galectin-12 is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed … top golf courses in vancouver bcWebAug 3, 2016 · Galectin-12 is a member of an animal lectin family with affinity for β-galactosides and containing consensus amino acid sequences. Here, we found that … picture places houstonpictureplane arlingtonWebSebaceous glands play an important role in maintaining the skin barrier function by producing lipids. Dysregulated lipid production in these glands may contribute to the pathogenesis of human skin diseases. Galectin-12, a member of the β-galactoside‒binding lectin family, is preferentially expressed in adipocytes, where it regulates adipogenesis … picture places in atlantaWebApr 14, 2024 · The galectin family of proteins has emerged as a viable therapeutic target for multiple indications, supported by years of study elaborating on their functions in the … top golf courses in wisconsin dells