Gm2a weight

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August undefined, 2024

WebThe GM2A gene provides instructions for making a protein called the ganglioside GM2 activator. This protein is necessary for the normal function of an enzyme called beta … WebOct 17, 2024 · Summary: The GM2A protein reduces neural firing and induces a loss of neurite integrity. Alzheimer’s disease (AD) currently has no cure and is predicted to affect …

GM2A Antibody - Cat. No. 62-067 ProSci

WebPredicted molecular weight. 19 kDa including tags. Amino acids. 33 to 193. Tags. His tag N-Terminus. Associated products. Related Products. Anti-GM2A antibody ... Defects in … WebJun 8, 2016 · GM2 gangliosidoses are autosomal recessive lysosomal storage diseases (LSDs) caused by mutations in the HEXA, HEXB and GM2A genes, which encode the human lysosomal β-hexosaminidase (Hex) α- and β-subunits, and GM2 activator protein (GM2A), respectively. These diseases are associated with excessive accumulation of … the texas house houston tx

Identiﬁcation of ganglioside GM2 activator playing a role in …

WebSep 1, 2016 · A DNA fragment encoding GM2A with a histidine-tag (10xHis) and the signal sequence of human lysosomal α-galactosidase A (GLA) was ligated into the pCXN 2 ... (w/v) acrylamide gel and silver staining with a Dodeca Silver Stain Kit (Bio-Rad). The molecular weight of GM2A was calculated based on those of the APRO markers (APRO Science, … WebOur GM2A polyclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression to confirm specificity to GM2A. Find the GM2A antibody that fits your needs. Choose from 1 of 14 GM2A antibodies, which have been validated in experiments with 2 publications and 34 images featured in ... WebWestern Blot: GM2A Overexpression Lysate (Adult Normal) [NBL1-11135] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GM2A. ... Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post ... thetexaslaserlady

Entry - *613109 - GM2 ACTIVATOR; GM2A - OMIM

National Center for Biotechnology Information

WebNational Center for Biotechnology Information WebExaminations at school age showed height and weight below the third centiles with head circumference at the 50th centile. Neurological examination disclosed mild spastic quadriparesis, limb ... GM2A encodes for the GM2 activator protein required for the extraction of lipids from bilayers, lipid solubilization, and presentation ... the texas injury firmWebSep 21, 2024 · Elevated ganglioside GM2 activator (GM2A) associates with reductions in both NI and MEA activity, and cell-derived GM2A alone is sufficient to induce a loss of … service triage

"WebGM2-gangliosidosis, AB variant is a rare inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord. Signs and symptoms of the AB variant … " - Gm2a weight

Gm2a weight

Recombinant Human GM2A protein (BSA and azide free) …

WebGM2-gangliosidosis, AB variant is a rare inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord. Signs and symptoms of the AB variant become apparent in infancy. Infants with this disorder typically appear normal until the age of 3 to 6 months, when their development slows and muscles used for movement ... WebGM2A Mouse anti-Human, Clone: 1E4D3, Proteintech 501736517 Print GM2A Mouse anti-Human, Clone: 1E4D3, Proteintech. Mouse Monoclonal Antibody. Manufacturer: Proteintech Group Inc 660801IG150UL View more versions of this product. Catalog No. 50-173 ...

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WebIMMUNOGEN: This GM2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human GM2A. CONJUGATE: Unconjugated; TESTED APPLICATIONS: WB; APPLICATION NOTE: For WB starting dilution is: 1:1000; PREDICTED MOLECULAR … WebDisclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation …

WebJul 6, 2016 · The GM2 activator is a low molecular weight, soluble protein that binds to the GM2 ganglioside, extracts it from the membrane, and solubilizes it as an activator/lipid … WebMolecular Weight: 164.16. Compare Product No. Description SDS Pricing; ... Hide. Match Criteria: Keyword, Product Name. GM2A. GM2 ganglioside activator. Synonyms: GM2 …

WebJul 9, 2015 · Height and weight were , 3% but. head circumference was normal. A cherry red spot was conspicuously. ... GM2A is an established gene for GM2-gangliosidosis, AB variant (MIM: 272750). WebMar 21, 2024 · GM2A (Ganglioside GM2 Activator) is a Protein Coding gene. ... tendons, ligaments, joints, and other connective tissue. The musculoskeletal system supports the weight of the body, maintains body …

WebThe GM2A gene provides instructions for making a protein called the ganglioside GM2 activator. This protein is necessary for the normal function of an enzyme called beta-hexosaminidase A, which plays a critical role in the brain and spinal cord (central nervous system). Beta-hexosaminidase A and the ganglioside GM2 activator protein work ...

WebDec 8, 2024 · cd00258. Location:32 → 193. GM2-AP; GM2 activator protein (GM2-AP) is a non-enzymatic lysosomal protein that acts as cofactor in the sequential degradation of … service tray on windows 10The protein encoded by this gene is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. GM2A is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T … service trimedx tcpWebUse a concentration of 1 - 2 µg/ml. Predicted molecular weight: 21 kDa. A 1 hour primary incubation is recommended for this product. Notes; WB ... Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB) [MIM:272750]; also known as Tay-Sachs disease AB variant. GM2-gangliosidosis is an autosomal recessive lysosomal storage disease ... service treadmill fitnessWebAlthough GM2A as a diagnostic and prognostic marker in BC should be carefully veriﬁed further, this study has established the potential role of GM2A in BC progression. B reast cancer is a major common cancer in women world … service truck 4 x 4WebPredicted molecular weight. 19 kDa including tags. Amino acids. 26 to 193. Tags. His tag C-Terminus. Additional sequence information. This product is the full length protein from aa 26 to 193. The signal peptide is not included (NP_000396.2). ... Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB) [MIM:272750]; also known as ... the texas homebuyerWebAug 25, 2024 · Establishing the Diagnosis. The diagnosis of GM2 activator deficiency is established in a proband with suggestive findings, normal beta-hexosaminidase A (HEX A) enzyme activity levels, and biallelic … service trips in the usWebDisclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation … the texas law dog animal rescue scholarship