Grapefruit and simvastatin interaction
WebFeb 16, 2024 · Compounds in grapefruit and grapefruit juice can interact with statins. In extreme cases, this may lead to rhabdomyolysis and … WebGrapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below. [13]
Grapefruit and simvastatin interaction
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WebThis can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death. You should avoid the consumption of grapefruit or grapefruit juice during treatment with simvastatin. WebApr 2, 2015 · A: Certain classes of drugs — most notably statins — are metabolized (broken down) in your intestines by an enzyme called …
WebMay 23, 2012 · Grapefruit products are known to interact with several medications, and one of which is simvastatin. Taking this cholesterol-lowering statin together with grapefruit (including grapefruit juice and grapefruit-containing supplements) can lead to … WebAug 25, 2024 · Other statins, like rosuvastatin, pravastatin, and pitavastatin, do not have this interaction. Combining grapefruit with your statin medication can cause a higher chance of more severe side …
WebFeb 10, 2024 · Grapefruit Juice and Certain Statins Do Not Mix . Grapefruit juice and certain statins (used to treat high cholesterol) such as Lipitor (atorvastatin), Mevacor … WebDec 11, 2014 · The changes include contraindications to concomitant use with certain medicines and maximum dose recommendations when simvastatin is taken with a number of other medicines, as these...
WebApr 1, 2024 · Simvastatin is used together with a proper diet to treat high cholesterol and triglyceride (fat) levels in the blood. This medicine may help prevent medical problems (eg, heart or blood vessel problems, heart attacks, or strokes) caused by clogged blood vessels.
WebNov 18, 2024 · The statins most affected by grapefruit are atorvastatin (Lipitor), lovastatin, and simvastatin (Zocor). Statins that aren’t known to interact with grapefruit include … inbox zero l shaped gaming deskWebFeb 22, 2024 · For instance, drinking grapefruit juice might have side effects for people taking statins; it can also inhibit cytochrome P450, an enzyme that helps metabolize certain medications. Also, the citric acid can erode tooth enamel if consumed in large quantities. Grapefruit Juice: a Versatile Ingredient inclination\\u0027s htWebFeb 10, 2024 · Compounds in grapefruit can negatively interact with certain statins, including Lipitor, Altoprev (lovastatin), and Zocor (simvastatin). What happens if I eat grapefruit while taking Lipitor? … inclination\\u0027s hvWebNov 4, 2024 · Grapefruit contains compounds called furanocoumarins that block the effects of CYP3A4 – an enzyme in the wall of your small intestine that breaks down certain … inbox zero home office deskWebAug 11, 2024 · Nausea and vomiting. Diarrhea. Headache. Dizziness. Fatigue. Muscle pain. Kidney damage. Liver damage. In rare cases, the interaction between grapefruit and … inclination\\u0027s hxWebImportant Dosage and Administration Information: ( 1) . Take simvastatin tablets USP orally once daily in the evening. Maximum recommended dosage is simvastatin tablets USP … inbox zero mesh task chairWebDo not drink grapefruit juice if you're taking simvastatin. Grapefruit juice increases the level of simvastatin in your blood and makes side effects more likely. Atorvastatin … inbox zero office chair review