Nettet15. jul. 2024 · Mitochondria are mobilized to varying degrees in response to intracellular energy requirements. In mouse oocytes, ATP increases rapidly in GVBD, decreases sharply after 1 h, and then increases slowly, which results in different ATP fluctuations during oocyte maturation [14,15]. Nettet4. apr. 2024 · Maternal mitochondria are the sole source of mtDNA for every cell of the offspring. Heteroplasmic mtDNA mutations inherited from the oocyte are a common cause of metabolic diseases and associated with late-onset diseases. However, the origin and dynamics of mtDNA heteroplasmy remain unclear.
IJMS Free Full-Text Lovastatin, an Up-Regulator of Low-Density ...
Nettet3. sep. 2010 · MII oocytes have been widely used to reprogram somatic cell nuclei, because during normal reproduction, sperm and oocyte nuclei are reprogrammed by the MII oocyte to produce totipotent zygotes. By contrast, results from our previous nuclear transfer studies have shown that the cytoplasm of GV stage oocytes have no … Nettet13. sep. 2024 · In premature porcine oocytes, a positive correlation was observed between mitochondrial DNA (mtDNA) copy number in the cumulus cells and that in oocytes reflecting the contribution of cumulus... the gold the inside story
Mitochondrial dynamics controlled by mitofusins define organelle ...
NettetNational Center for Biotechnology Information Nettet24. mar. 2024 · Clpp Clpp knockout mice was further deteriorated with dramatic impairment of mitochondrial distribution and function including elevated ROS level, decreased mitochondrial membrane potential, respiratory chain … Nettet12. des. 2024 · As the most abundant organelles in oocytes, mitochondria play an important role in maintaining oocyte quality. Here, we report that March5, encoding a mitochondrial ubiquitin ligase that promotes mitochondrial elongation, plays a critical role in mouse oocyte meiotic maturation via regulating mitochondrial function. the gold thread