WebMutations in theLMNAgene encoding nuclear lamins A/C cause a diverse array of tissue-selective diseases, with the heart being the most commonly affected organ. Despite progress in understanding the molecular perturbations emanating fromLMNAmutations, WebThbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy Nature Communications . 10.1038/s41467-021-24215-4 . 2024 . Vol 12 (1) . Author(s): Davy …

Myeloid-Derived TSP1 (Thrombospondin-1) Contributes …

WebThrombospondin 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. THBS1 (THBS, THBS-1, TSP, TSP-1, TSP1) Protein classi. … WebThese findings were confirmed in human islets silenced for THBS1 (Fig. 1, C and D).Apoptosis was also detected by immunostaining for cleaved caspase 3 in THBS1 … cannot load library qt5

21825 - Gene ResultThbs1 thrombospondin 1 [ (house mouse)]

WebGene: THBS1; thrombospondin 1. Aliases: TSP, THBS, TSP1, TSP-1, THBS-1. Location: 15q14. Summary: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. WebDescription. TSP is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. TSP can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. It has been shown to play roles in … WebThe present disclosure provides antigen-binding molecules that bind to HER3 for the treatment or prevention of cancers, compositions comprising said molecules, and therapeutic and prophylactic methods using said molecules. fl1series insulated heated cabinet